anadrol (oxymetholone)
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oxymetholone 50mg
oxymetholone tablets
ANADROL-50
Anadrol is a derivative of dihydrotestosterone, but itself resembles estrogen. It will bring estrogen-like side effects. It belongs to 17-AA steroids and has certain liver toxicity. It can quickly increase strength, increase girth and relieve joint pain, improve the pump feeling during training, and have a strong protein synthesis ability and androgenic properties. Can quickly gain weight in a short period of time. Therefore, it is more suitable for use in the muscle-building phase.
50mg/tablet × 50 tablets/box
Dosage: 1~2 capsules/day
Packaging: Tablets
Cycle: 3 to 6 weeks
Introduction
Anadrol is an oral anabolic steroid derived from dihydrotestosterone. More specifically, it is nothing more than methyldihydrotestosterone with the addition of 2-hydroxymethylene. This produces a steroid-like substance with markedly different activities than metabolone, but it is difficult to compare between the two. For starters, Anadrol is a very potent anabolic hormone. Since these molecules are not very stable in the high enzyme (3-alpha hydroxysteroid dehydrogenase) environment of muscle tissue, where both DHT and Metanolone are very weak. Oxygen free radicals remain highly active here, and are more anabolic than testosterone or methyltestosterone, as reported in standard animal assays. Such determinations show that the androgenicity of Anadrol is still very low.
Many consider Anadrol to be the most powerful steroid commercially available. A novice who uses steroids experimenting with the drug may gain 20 to 30 pounds, and can usually achieve this within 6 weeks of use. This steroid causes the body to store a lot of water, so a large part of this weight gain will be water. This usually has little to no effect on the user, who all feel their muscles are big and strong while taking Anadrol. Although the slick look you get from water storage is often unattractive, it can greatly improve size and strength. Muscles are fuller, more contractile and provide a degree of protection consisting of extra water and connective tissue. This will allow for more elasticity and will hopefully reduce the chances of serious weightlifting injuries. However, it should be noted that a very rapid gain in mass may also place too much stress on the connective tissue. Tears of pectoral and biceps tissue are often associated with heavy lifting
history:
Anadrol first appeared in 1959. The drug became available by prescription in the United States in the early 1960s and was sold under the brand names Anadrol-50 (Syntex) and Androyd (Parke Davis & Co.). Syntex became the agent and held the patent until it expired many years later. The drug was originally approved for conditions requiring anabolic effects. Indicated uses include senile debilitation, chronic underweight states, maintenance of lean body mass before and after surgery, recovery from infection, gastrointestinal disorders, osteoporosis, and general catabolic conditions. The recommended dose for this use is usually 2.5 mg once three times daily. The drug was initially available as 2.5mg, 5mg, or 10mg tablets.
Provide specifications:
Ingredients and dosage may vary by country and manufacturer. Most brands contain 50mg of steroids per tablet.
Structural features:
Anadrol is a modified form of dihydrotestosterone. It differs from 1) the addition of a methyl group at the 17-alpha carbon, which helps protect the hormone during oral administration, and the introduction of a 2-hydroxymethylene group can inhibit the metabolism of the 3-HSD enzyme, greatly enhancing the methyl dihydro Anabolic and relative biological activity of testosterone
Side effects (estrogen):
Anadrol is a highly estrogenic steroid. Gynecomastia is often a problem during treatment and may appear early in a cycle (especially when higher doses are used). At the same time, water retention can also become an issue, and muscle definition can be significantly lost due to subcutaneous water storage and fat accumulation. To avoid strong estrogenic side effects, an anti-estrogen such as anastrome, exemestane may be needed
It is important to note that Anadrol is not directly converted to estrogen in the body. This steroid is a derivative of dihydrotestosterone and therefore cannot aromatize. Antiaromatic compounds such as Cytadren and Arimidex also do not affect the relative estrogenicity of this steroid. It has been suggested that the high level of estrogenic activity contained in Anadrol is actually due to the fact that it is a progesterone-like drug, like nandrolone. The side effects of estrogen and progestin are very similar, which makes this explanation possible. However, one medical study examining the progestational activity of Anadrol determined that it had no such activity. With such findings, it seems most likely that Anadrol activates estrogen receptors similar to, and possibly even stronger than, the estrogen androgen methyltriol.
Side effects (androgenic):
Although Anadrol is classified as an anabolic steroid, the substance can still have androgenic side effects. These can include oily skin, acne, and bouts of body/facial hair growth. Higher doses are more likely to cause this side effect. Anabolic/androgenic steroids may also accelerate hair loss in men. Women are also warned of the potentially exacerbating effects of anabolic/androgenic steroids. These may include deepening of the voice, menstrual irregularities, changes in skin texture, facial hair growth, and clitoral enlargement. Although Anadrol is classified as an anabolic steroid, it does retain a significant androgenic component.
Interestingly, Anadrol does show a tendency to convert to DHT in the body, although this does not occur via 5-alpha reductase. Anadrol is already a dihydrotestosterone based steroid, so this change does not occur. Anadrol is differentiated from DHT by the addition of 2-hydroxymethylene in addition to the added c-17 alpha alkylation (discussed below). This grouping removes the metabolism, reducing Anadrol to 17α-Methyldihydrotestosterone (Mitaolone). There is no doubt that this biotransformation contributes at least in part to the androgenicity of this steroid. Note that since 5-alpha reductase is not involved, the relative androgenicity of anadrol is unaffected compared with concomitant finasteride or dutasteride.
Side Effects (Hepatotoxicity):
Anadrol is a c17-alpha alkylated compound. This alteration protects the drug from liver activation, resulting in a very high proportion of the drug entering the bloodstream after oral administration. C17-alpha-alkylated anabolic/androgenic steroid, hepatotoxic. Prolonged or heavy use may cause liver damage. In rare cases, life-threatening dysfunction may occur. Regular visits to a physician are recommended during each cycle to monitor liver function and overall health. C17-alpha alkylated steroid intake is usually limited to 6-8 weeks to avoid liver damage.
Anadrol has a saturated A-ring, slightly reducing the relative hepatotoxicity. However, the agent, especially at commonly used doses, can present significant hepatotoxicity in users. A study of 31 elderly men administered 50 mg or 100 mg weekly for 12 weeks. In patients taking 100 mg, liver enzymes (transaminases AST and ALT) increased significantly. A second study of 30 subjects given a daily dose of 50 mg has demonstrated a 17% increase in gamma-glutamyltransferase (GGT), a 10% significant increase in bilirubin, and a 20% increase in serum albumin. One patient developed a liver tumor and possibly hepatic hepatitis, a life-threatening adverse condition characterized by congested cysts in the liver. A small number of other cases of hepatitis have been associated with Anadrol, so the possibility of hepatotoxicity should still be carefully considered before use.
Side Effects (Cardiovascular):
Anabolic/androgenic steroids can have deleterious effects on serum cholesterol. This includes a tendency to decrease HDL (good) cholesterol values and increase LDL (bad) cholesterol values, which may shift HDL to LDL balance. The relative effects of anabolic/androgenic steroids on serum lipids depend on dose, route of administration (oral vs parenteral), type of steroid (aromatizable or non-aromatizable), and level of resistance to hepatic metabolism. Anabolic/androgenic steroids may also adversely affect blood pressure and triglycerides, reduce endothelial relaxation, and cause left ventricular hypertrophy, which may increase the risk of cardiovascular disease and myocardial infarction.
Due to its structural resistance to hepatic breakdown and route of administration, oxymethylflavones have a strong effect on cholesterol in the liver. A study of a group of elderly men administered 50 mg or 100 mg weekly for 12 weeks conclusively showed no significant increase in LDL cholesterol but showed significant suppression of HDL cholesterol (in the 50 mg and 100 mg groups 19 and 23 points lower, respectively). Anadrol should be used in patients with high cholesterol or a family history of heart disease only after careful consideration.
To help reduce cardiovascular strain, it is recommended to maintain an active cardiovascular exercise program and to consistently reduce saturated fat intake and minimize cholesterol and simple carbohydrate intake during AAS use. Supplementation with fish oil (4 grams per day) and a natural cholesterol/antioxidant formula like Lipid Stabil or a product with similar ingredients is also recommended.
Side effects (testosterone suppression):
When taken in doses sufficient to promote muscle gain, all anabolic/androgenic steroids are expected to suppress endogenous testosterone production. Without the intervention of testosterone-stimulating substances, testosterone levels should return to normal within 1-4 months of drug splitting. Note that hypogonadism may be secondary to steroid abuse, requiring medical intervention.
Be aware that when Anadrol is discontinued, the resulting conditions can be as powerful as the post-cycle results. First, the level of water retention will decrease rapidly, significantly reducing the user's weight. This should be expected and nothing to be concerned about. Often the greatest concern is the restoration of endogenous testosterone production with an appropriate PCT regimen (PCT cycle therapy). Some people choose to switch to milder injectables such as Deca Durabolin (nandrolone decanoate) for a few weeks before starting. This is to "harden" the new muscles and can prove to be an effective practice, at least from a psychological standpoint. Some loss of mass may occur when making the switch, although the end result will generally preserve more (mass) muscle mass. This decline begins with a decrease in water retention, by a decrease in hormones a few weeks later. Remember to use adjuvant medications as testosterone production will not rebound during Deca treatment.
Treatment (generic):
Research suggests that taking oral anabolic steroids with food may decrease their bioavailability. This is caused by the fat-soluble nature of steroid hormones, which may dissolve some drugs with undigested dietary fat, reducing absorption from the gastrointestinal tract. For maximum utilization, this steroid should be taken on an empty stomach.
Treatment (male):
Early prescribing guidelines for Anadrol suggested a dose of 1-5 mg/kg body weight per day for the treatment of anemia, although a dose of 1-2 mg/kg was usually adequate. A 175-pound person takes about 150 mg per day at a dose of 2 mg/kg of body weight. In some other countries, it is recommended to limit the dose of anadrol to 100 mg once daily. Treatment is usually at least three to six months. When used for strength or performance enhancement purposes, effective oral daily doses are in the range of 25-150 mg, but to be taken in cycles not exceeding 6-8 weeks to minimize hepatotoxicity. This level is enough to significantly increase muscle mass and strength. Higher doses are rarely administered due to the strong estrogenic properties of the drug and the high potential for hepatotoxicity.
The off-season cycle is generally 50mg per day, and high-level athletes may reach 150mg per day.
lifetimesteorids Team