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CAS 120511-73-1Pharmaceutical Raw Materials Anastrozole Arimidex Steorids Powder
Description:
Anastrozole
Alias: Arimidex
CAS No: 120511-73-1
MF: C17H19N5
MW: 293.37
Melting Point: 81.0~84.0°C
Anastrozole / Arimidex Medicine Injectable Anabolic Steroid Hormones Without Side Effects
Purity: 99%
Appearance: White Crystalline Powder
How effective is anastrozole in preventing breast cancer?
1920 women were randomly assigned to 5 years anastrozole and 1944 to placebo. After a median follow-up of 131 months (IQR 105-156), a 49% reduction in breast cancer was observed for anastrozole (85 vs 165 cases, hazard ratio [HR] 0·51, 95% CI 0·39-0·66, p<0·0001).
Does anastrozole weaken your immune system?
Does hormone therapy affect the immune system? Taking hormone therapy, including tamoxifen, letrozole, anastrozole, exemestane and goserelin, does not affect your immune system.
Is 5 years on anastrozole enough?
"After 5 years of standard endocrine therapy, 2 additional years of anastrozole are sufficient," said Michael Gnant, director and chairperson of the department of surgery at the Comprehensive Cancer Center at the Medical University of Vienna, who presented the research.
Is it better to take anastrozole in the morning or at night?
If hot flashes are troublesome: • Take your anastrozole at bedtime. hot flashes continue to bother you. There may be medications available. Muscle or joint pain may occur a few days after your treatment
COA
Items | Standard | Results |
Description | White crystalline powder | Complies |
Identification | IR | Conform with standard IR |
HPLC | Conform with standard HPLC | |
Reactive | Conform | |
Solubility | Freely soluble in methanol,acetone,ethanol and tetrahydrofuran.And very soluble in acetonitrile | Complies |
Total Impurity | max.0.5% | 0.18% |
Total Unspecified Impurity | max. 0.2% | 0.08% |
Individual unspecified impurlty | max. 0.1% | 0.05% |
Related compound B | max. 0.2% | 0.07% |
Related compound C | max. 0.2% | 0.04% |
Related compound D | max. 0.1% | 0.05% |
Related compound E | max. 0.1% | 0.06% |
Limit of cyclohexane | max. 0.08% | ND |
Limit of ethylacetate | max. 0.1% | 0.07% |
Melting point | 81.0~84.0℃ | 82.5~83.2℃ |
Water | max. 0.3% | 0.21% |
Residue on ignition | max. 0.1% | 0.07% |
Heavy Metals | max.0.001% | Complies |
Assay(HPLC) | 98.0%~102.0% | 99.80% |
Storage | Cool and dry | |
Conclusion | It complies to USP32 . |
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